Advancing Treatment for Kidney Disease Kidney disease encompasses a range of conditions that can lead to kidney failure, dialysis or transplantation if left untreated. CSL Vifor develops and delivers targeted therapies for chronic kidney disease and rare kidney disorders. We have developed a broad range of therapies and medicines to preserve renal function, manage complications and improve patients’ quality of life with kidney disease. CSL also continues to advance research into the long-term management of chronic kidney disease. Helping Patients with IgA Nephropathy ‘Know Their Numbers’ On World Kidney Day 2026, CSL reaffirmed its commitment to supporting the kidney disease community and improving outcomes for people living with IgA nephropathy (IgAN). Central to managing IgAN is understanding the three ‘numbers’ that matter most: proteinuria, estimated glomerular filtration rate (eGFR) and blood pressure. To help patients take a more active role in managing their condition, CSL Vifor launched the Navigate Your Numbers campaign in collaboration with the U.K.’s National Kidney Federation. The campaign empowers people living with IgAN to better understand these three key measures, track changes over time and have more informed conversations with their healthcare team about disease progression. This booklet has been created by CSL Vifor in collaboration with the National Kidney Federation and people living with and treating IgA nephropathy. NAVIGATE YOUR NUMBERS in IgA nephropathy TRACKING YOUR NUMBERS: A guide of key numbers for people with IgA nephropathy UK-NP-2500178 | September 2025 Iron is an essential mineral involved in many vital functions throughout the body. When your body has the iron levels it needs, you have the foundation for energy, focus and overall wellbeing. Iron deficiency is one of the most common complications of chronic kidney disease, heart failure and inflammatory disorders. However, there are many other reasons a person may find themselves low in iron, such as inadequate dietary intake, heavy periods or poor gut absorption. It’s surprisingly common in women of reproductive age, affecting 11–35% of non-pregnant women,* yet it often slips under the radar. Treatment of iron deficiency is particularly important for relieving day-to-day symptoms such as fatigue, headaches, shortness of breath and ‘brain fog’. This year, CSL Vifor saw a need to help women better understand the prevalence of iron deficiency and why iron matters for good health. We launched a disease awareness campaign called Her Iron Matters, including the educational website herironmatters.com, to draw attention to this common health issue and encourage more women to get checked. As of August 2026, the campaign has reached 6.2 million women, garnering more than 300,000 website visits and an above- benchmark engagement rate of 32%. *Source: Burns et al., 2025 (doi.org/10.1016/j.jtemb.2025.127684) Overcoming Iron Deficiency in More Ways Than One | Introduction | For Patients | For Science | For Society | Looking Forward CSL IMPACT REPORT 2026 | 15
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