3. World Health Organization (2025) Influenza (seasonal). https://www.who.int/news-room/factsheets/detail/influenza-(seasonal) 4. Centre for Disease Control and Prevention (2025) Severity, Disease Burden, and Prevented Burden for the 2024-2025 Influenza Season https://www.cdc.gov/acip/downloads/slides-2025-06-25-26/03dugan-influenza-508.pdf 5. Centre for Disease Control and Prevention (2025) Preliminary Flu Vaccine Effectiveness (VE) Data for 2024-2025 https://www.cdc.gov/flu-vaccines-work/php/effectiveness-studies/2024-2025.html Vaccines We specialise in discovering, developing and delivering vaccines, with a focus on influenza. Seasonal influenza (the flu) is an acute respiratory infection caused by influenza viruses, common in all parts of the world.3 In the U.S. alone, the CDC estimates that influenza vaccination prevented 12 million illnesses, 5.7 million doctor visits and 240,000 hospitalisations in the 2024–25 season.4 Data from the 2024–2025 season shows the vaccine continues to offer strong protection – reducing the chance of needing medical care or being hospitalised for influenza by up to 78%, especially in children and teenagers.5 Most people who get sick with influenza will have a mild illness. However, some people – such as people over 65 years of age, young children, pregnant women and people with chronic illnesses – are more likely to get influenza complications that can result in hospitalisation and sometimes death. Our bodies and the influenza virus are in a never-ending race. As our immune system evolves to avoid infection, the virus adapts to evade our immune system. Influenza spreads best when temperatures and humidity are low, so the influenza season coincides with the winter months in all different parts of the globe. This is why we need new influenza vaccines each influenza season – and why we are always working to stay ahead of the mutating virus. >101m doses of influenza vaccines delivered in FY2025 helping prevent an estimated 15,284,430 illnesses, 220,349 hospitalisations and 37,572 deaths 15 Limited Our Impact 2025 About CSL From our CEO Lifesaving Medicines Science and Medicine Legacy Healthier Communities
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