Improving Blood Health, Globally Patient blood management practice addresses the relationship between iron deficiency, anaemia and surgery – a time when blood loss must be managed carefully. Having anaemia prior to surgery is associated with increases in mortality, surgical complications, the need for blood transfusions and longer hospital stay.1 As a member of the Blood & Beyond initiative, we’re working with governments and hospitals to enhance patient outcomes through advocating for patient blood management – an approach focused on managing and preserving a patient’s own blood. The benefits include: • diagnosing and appropriately correcting anaemia and iron deficiency, • minimising blood loss and bleeding, and • supporting patients with appropriate treatment instead of reverting to blood transfusion. Implementing one patient blood management program led to a 28% reduction in mortality, a 21% reduction in infection, and a 15% reduction in time spent in hospital.2 Through the Blood & Beyond initiative, we advocate for patient blood management by raising awareness of its enduring benefits and publishing scientific materials aimed at helping hospitals to implement these practices. Treatments for Iron Deficiency Iron is needed for the proper functioning of many systems in the human body, including the heart, muscles and red blood cells. It also plays a vital role in the immune system, the development of the brain and cognitive function. Iron deficiency is a very common condition. Studies show that it affects up to one third of the global population. Despite its high occurrence and its potentially serious consequences for patients’ health, iron deficiency remains an overlooked, under-diagnosed and under-treated condition. We have pioneered a range of iron-based medicines to treat iron deficiency, helping patients affected by these conditions to live better, healthier lives. >33m patient-years of our high-dose IV iron across heart failure, major elective surgery, women’s health, nephrology and gastroenterology patients >38m patient-years of our low‑dose IV iron, mainly in nephrology patients 1. Ranucci, M., Ballotta, A., La Rovere, M. T., Castelvecchio, S., & Menicanti, L. (2013). Postoperative blood transfusion and outcome in adult cardiac surgery. Annals of Thoracic Surgery, 96(2), 478–485. 2. Frank, S. M., Tran, K. M., Fleisher, L. A., & Ness, P. M. (2017). Reducing unnecessary blood transfusions: A 10-year experience. Anesthesiology, 127(4), 754–764. Pregnancy creates extra demand for certain nutrients including iron. These treatments are measured in ‘Patient-Years’ – a measurement used in epidemiology and clinical research to quantify the amount of time patients are exposed to a treatment. Since market authorisation and as of the end 2024, we delivered: 12 Limited Our Impact 2025 About CSL From our CEO Healthier Communities Science and Medicine Legacy Lifesaving Medicines
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