Treatments for Kidney Disease People living with chronic kidney disease face a long and difficult journey associated with multiple and varying conditions and complications that severely impact their quality of life and life expectancy. We have developed a broad range of therapies and medicines to preserve renal function, manage complications and improve patients’ quality of life with kidney disease – from early stages through to late stage and dialysis. 184,000 patients treated globally for diseases associated with kidney disease such as hyperphosphatemia and hyperkalemia An abnormal elevation of phosphorus levels – hyperphosphatemia – in the blood, is a common and serious condition in chronic kidney disease patients on dialysis, because, due to severe impairment, kidneys cannot remove extra phosphorus, which can pose significant health risks, including mineral and bone disorder. Hyperkalaemia is defined as abnormally elevated levels of potassium in the blood, a serious condition in cardio-renal patients that can be responsible for cardiac arrhythmias leading to cardiac arrest and death. 11,000 patients treated globally for chronic kidney disease‑associated pruritus across the U.S., Europe and Australia This is a condition characterised by severe itching in patients with chronic kidney disease, particularly in advanced stages. In FY2025, our medicines treated approximately: 1,400 patients treated with our recently approved therapy for IgA nephropathy (Berger’s disease) in Europe in only a few months This is kidney disease caused by deposits of the protein immunoglobulin A (IgA) in the kidneys. This leads to inflammation that can impair the kidneys’ ability to filter waste from the blood. 10,000 patients treated globally (excluding the U.S.) for ANCA‑associated vasculitis Anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis is a systemic disease in which over-activation of the complement pathway further activates neutrophils, leading to inflammation and destruction of small blood vessels. This results in organ damage and failure, with the kidney as the major target, and is fatal if not treated. 9 Limited Our Impact 2025 About CSL From our CEO Healthier Communities Science and Medicine Legacy Lifesaving Medicines
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