CSL Annual Report 2024

Pandemic is the worldwide spread of a disease. Pharmacokinetics is the study of how the body processes drugs, including their absorption, distribution, metabolism, and elimination. Pharmacovigilance is the practice of monitoring the effects of medical drugs after they have been licensed for use, especially in order to identify and evaluate previously unreported adverse reactions. Plasma is the yellow-coloured liquid component of blood in which blood cells are suspended. Primary immunodeficiency (PID) is an inherited condition where there is an impaired immune response. It may be in one or more aspects of the immune system. Prophylaxis is the action of a vaccine or drug that acts to defend against or prevent a disease. Prothrombin complex is a combination of blood clotting factors, including prothrombin, factors VII, IX, and X, which work together to facilitate blood clot formation. Pruritus is the medical term for itching, which can occur due to various reasons such as dry skin, allergies, insect bites, or underlying medical conditions like liver or kidney disease. Quadrivalent influenza vaccine is a vaccine that offers protection against four different influenza virus strains. Recombinants are proteins prepared by recombinant technology. Procedures are used to join together segments in a cell‑free system (an environment outside a cell organism). sa-mRNA is a technology designed to enhance protein production within cells. With this technology, the mRNA incorporates an element that allows the host cell to make copies of the administered mRNA, which in turn increases the amount of protein that the cell produces. Scope 1 emissions are controlled by the company, for example, emissions from combustion in owned or controlled boilers, furnaces, or vehicles. Scope 2 emissions are released as a result of one or more activities that generate electricity, heating, cooling or steam that is consumed by the facility, but that do not form part of the facility. Scope 3 emissions are the result of activities from assets not owned or controlled by the reporting organisation, but that the organisation indirectly affects in its value chain. Scope 3 emissions include all sources not within an organisation’s Scope 1 and 2 boundary. Secondary immunodeficiency (SID) is when the immune system becomes weakened due to factors like medical treatments, medications, infections, or other health conditions. Subcutaneous is the administration of drugs or fluids into the subcutaneous tissue, which is located just below the skin. Thrombosis is the formation of a blood clot within a blood vessel, which can obstruct blood flow and lead to serious complications if the clot dislodges and travels to other parts of the body. Trivalent influenza vaccine is a vaccine that offers protection against three different influenza virus strains. von Willebrand disease (vWD) is a hereditary disorder caused by defective or deficient von Willebrand factor, a protein involved in normal blood clotting. Zoonotic refers to diseases that can spread from animals to humans. Glossary 160 Limited Annual Report 2023/24

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