CSL Ltd Annual Report 2020

Pharmacovigilance is the practice of monitoring the effects of medical drugs after they have been licensed for use, especially in order to identify and evaluate previously unreported adverse reactions. Plasma is the yellow-coloured liquid component of blood in which blood cells are suspended. Primary immunodeficiency (PI) is an inherited condition where there is an impaired immune response. It may be in one or more aspects of the immune system. Prophylaxis is the action of a vaccine or drug that acts to defend against or prevent a disease. Q fever is a bacterial infection that can cause a severe flu-like illness. It is spread to humans by animals, most commonly sheep, goats and cattle. Quadrivalent influenza vaccine is a vaccine that offers protection against four different influenza virus strains. Recombinants are proteins prepared by recombinant technology. Procedures are used to join together segments in a cell-free system (an environment outside a cell organism). Sickle cell disease is an inherited group of disorders, in which red blood cells contort into a sickle shape. The cells die early, leaving a shortage of healthy red blood cells and can block blood flow causing pain. Subarachnoid haemorrhage is the sudden leaking of a blood vessel over the surface of the brain. Subcutaneous is the administration of drugs or fluids into the subcutaneous tissue, which is located just below the skin. Thrombocytopenia is a condition characterised by a decrease in the number of thrombocytes, also called platelets, in the blood, thus reducing the ability of the blood to clot. Trivalent influenza vaccine is a vaccine that offers protection against three different influenza virus strains. von Willebrand disease (vWD) is a hereditary disorder caused by defective or deficient von Willebrand factor, a protein involved in normal blood clotting. CSL Limited Annual Report 2020 149